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Willingness to Receive COVID-19 Vaccination Among People Living with HIV and Aids in China: Nationwide Cross-Sectional Online Survey
From the Introduction: "The World Health Organization (WHO) confirmed that HIV infection is a significant independent risk factor for both severe COVID-19 [coronavirus disease 2019] presentation at hospital admission and in-hospital mortality [...]. It is essential to take additional measures to prevent people living with HIV and AIDS (PLWHA) from contracting COVID-19. The COVID-19 vaccine offers the best hope for ending the pandemic. Simulation experiments showed that when vaccine efficacy was 80%, 75% coverage could end the COVID-19 pandemic without any other control measures [...]. A relatively small number of PLWHA were involved in phase III COVID-19 vaccine trials. The Pfizer study and the Oxford/AstraZeneca study recruited 196 and 157 PLWHA, respectively; however, the data on vaccine efficacy for PLWHA was not included in the publications that led to their approval in the United States and the United Kingdom [3,4]. The Moderna study included 176 PLWHA [...]. Of the PLWHA in the Moderna study, one person who received the placebo and none who received the vaccine developed COVID-19. The Janssen (Johnson & Johnson) study included 1218 PLWHA [...]. Two PLWHA who received the vaccine and four who received the placebo developed COVID-19. There were 201 PLWHA in the Novavax study; the overall vaccine efficacy was 49.4%, with a higher efficacy when PLWHA were excluded from the analysis (60%) [...]."
JMIR Publications
Huang, Xiaojie; Yu, Maohe; Fu, Gengfeng . . .
2021-10-21
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