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Pakistan's Response to COVID-19: Overcoming National and International Hypes to Fight the Pandemic
From the Document: "COVID-19 [coronavirus disease 2019] cases were reported from Islamabad and Karachi on February 26, 2020. Pakistan being one of the most densely populated countries in Asia, with a population of 204.65 million, and Karachi being the largest metropolitan city in Pakistan, has been greatly vulnerable to this outbreak. Owing to its present economic condition, health care resources, and the occurrence of previous outbreaks, the Centers for Disease Control and Prevention had already issued a level 3 warning for international travelers to Pakistan. The administration had a huge responsibility to constrain the spread through a timely response and the adoption of appropriate measures to avoid any major catastrophe. The disease was initially difficult to contain, especially because of noncompliance of the general population to the necessary measures and timely reporting of symptoms. Within 45 days, on April 10, 2020, Pakistan reported 4601 confirmed cases with a death toll approaching 66 individuals."
JMIR Publications
Akhtar, Hashaam; Afridi, Maham; Akhtar, Samar . . .
2021-05-19
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Notes from the Field: The Combined Effects of Tocilizumab and Remdesivir in a Patient with Severe COVID-19 and Cytokine Release Syndrome
From the Abstract: "SARS-CoV-2 [severe acute respiratory syndrome coronavirus 2] is known to cause severe bilateral pneumonia and acute respiratory distress syndrome or COVID-19 [coronavirus disease 2019] in patients, which can be debilitating and even fatal. With no drugs or vaccines available yet, a wide range of treatment regimens used are being repurposed. The need of the hour is to analyze various currently available regimens and devise a treatment plan that is most effective for COVID-19. Here we describe the case of a 68-year-old man with hypertension and diabetes, exhibiting symptoms of cough and shortness of breath, who presented at the emergency department of our hospital. Chest computed tomography revealed bilateral ground glass opacities that were indicative of COVID-19, and a computed tomography score of 24 was indicative of severe pulmonary pneumonia. He tested positive for COVID-19. His treatment regimen included the use of convalescent plasma, oxygen therapy, steroids, high-dose antibiotics, broad-spectrum antiviral remdesivir, and anti-interleukin-6 monoclonal antibody (Tocilizumab) at various stages of the disease. Oxygen supplementation was required at the time of admission. The patient initially developed a cytokine release storm, and oxygen supplementation was initiated to manage his condition. Supportive care and multiple treatment regimens were used to successfully recover the patient's health. With a rapid increase in number of confirmed cases worldwide, COVID-19 has become a major challenge to our health care system. With no available vaccines currently, the establishment of a combination of therapeutic drugs that effectively reduce disease progression is of utmost importance." This article can also be found here on the Journal of Medical Internet Research (JMIR) Public Health and Surveillance website: [https://publichealth.jmir.org/2021/5/e27609].
JMIR Publications
Ali, Sabahat; Khalid, Sundas; Afridi, Maham . . .
2021-05-19
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