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Universal Screening for SARS‐CoV‐2 Infection: A Rapid Review
From the Abstract: "Coronavirus disease 2019 (COVID-19) is caused by the novel betacoronavirus, severe acute respiratory syndrome coronavirus-2 (SARSCoV-2). Most people infected with SARS-CoV-2 have mild disease with unspecific symptoms, but about 5% become critically ill with respiratory failure, septic shock and multiple organ failure. An unknown proportion of infected individuals never experience COVID-19 symptoms although they are infectious, that is, they remain asymptomatic. Those who develop the disease, go through a presymptomatic period during which they are infectious. Universal screening for SARS-CoV-2 infections to detect individuals who are infected before they present clinically, could therefore be an important measure to contain the spread of the disease. We conducted a rapid review to assess (1) the effectiveness of universal screening for SARS-CoV-2 infection compared with no screening and (2) the accuracy of universal screening in people who have not presented to clinical care for symptoms of COVID-19." This webpage gives the user the option to download a full, standard (excludes data and analyses, and appendices), or a summarized report in pdf format.
John Wiley & Sons, Ltd.; Cochrane (Organization)
Viswanathan, Meera; Kahwati, Leila C.; Jahn, Beate . . .
2020-09-15?
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Quarantine Alone or in Combination with Other Public Health Measures to Control COVID-19: A Rapid Review (Review)
From the Plain Language Summary: "We wanted to find out whether and how effectively quarantine stops COVID-19 [coronavirus disease] spreading and if it prevents death. We wanted to know if it was more effective when combined with other measures, such as closing schools. We also wanted to know what it costs. [...] COVID-19 is spreading rapidly, so we needed to answer this question as quickly as possible. This meant we shortened some steps of the normal Cochrane Review process. Nevertheless, we are confident that these changes do not affect our overall conclusions. We looked for studies that assessed the effect of any type of quarantine, anywhere, on the spread and severity of COVID-19. We also looked for studies that assessed quarantine alongside other measures, such as isolation, social distancing, school closures and hand hygiene. COVID-19 is a new disease, so, to find as much evidence as possible, we also looked for studies on similar viruses, such as SARS (severe acute respiratory syndrome) and MERS (Middle East respiratory syndrome). Studies measured the number of COVID-19, SARS or MERS cases, how many people were infected, how quickly the virus spread, how many people died, and the costs of quarantine."
John Wiley & Sons, Inc. publication
Nussbaumer-Streit, Barbara; Mayr, Verena; Dobrescu, Andreea . . .
2020
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