Biomedical Research: Observations on DOD's Management of Congressionally Directed Medical Research Programs [open pdf - 8MB]
From the Introduction: "The Department of Defense (DOD) is among the United States' largest federal sponsors of biomedical research, which contributes to discoveries of new drugs, vaccines, medical services, and other approaches for preventing, diagnosing, and treating diseases, conditions, and injuries.  For fiscal year 2021, Congress appropriated nearly $2.4 billion for the Defense Health Program for research, development, test and evaluation, which includes biomedical research.  Of that amount, about $1.5 billion funded DOD's Congressionally Directed Medical Research Programs (CDMRP), including 36 research program areas such as cancers, alcohol and substance abuse disorders, and spinal cord injury.  CDMRP has grown since its initial appropriation of $210 million in 1992 (about $367 million in fiscal year 2021 dollars) to fund a breast cancer research program."
Government Accountability Office: https://www.gao.gov/