ABSTRACT

Willingness to Receive COVID-19 Vaccination Among People Living with HIV and Aids in China: Nationwide Cross-Sectional Online Survey   [open pdf - 792KB]

From the Introduction: "The World Health Organization (WHO) confirmed that HIV infection is a significant independent risk factor for both severe COVID-19 [coronavirus disease 2019] presentation at hospital admission and in-hospital mortality [...]. It is essential to take additional measures to prevent people living with HIV and AIDS (PLWHA) from contracting COVID-19. The COVID-19 vaccine offers the best hope for ending the pandemic. Simulation experiments showed that when vaccine efficacy was 80%, 75% coverage could end the COVID-19 pandemic without any other control measures [...]. A relatively small number of PLWHA were involved in phase III COVID-19 vaccine trials. The Pfizer study and the Oxford/AstraZeneca study recruited 196 and 157 PLWHA, respectively; however, the data on vaccine efficacy for PLWHA was not included in the publications that led to their approval in the United States and the United Kingdom [3,4]. The Moderna study included 176 PLWHA [...]. Of the PLWHA in the Moderna study, one person who received the placebo and none who received the vaccine developed COVID-19. The Janssen (Johnson & Johnson) study included 1218 PLWHA [...]. Two PLWHA who received the vaccine and four who received the placebo developed COVID-19. There were 201 PLWHA in the Novavax study; the overall vaccine efficacy was 49.4%, with a higher efficacy when PLWHA were excluded from the analysis (60%) [...]."

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Date:
2021-10-21
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Copyright:
2021 Xiaojie Huang, Maohe Yu, Gengfeng Fu, Guanghua Lan, Linghua Li, Jianzhou Yang, Ying Qiao, Jin Zhao, Han-Zhu Qian, Xiangjun Zhang, Xinchao Liu, Xia Jin, Guohong Chen, Hui Jiang, Weiming Tang, Zixin Wang, Junjie Xu. Posted here with permission. Document is under a Creative Commons license and requires proper attribution and noncommercial use to be shared: [https://creativecommons.org/licenses/by/4.0/].
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JMIR Publications: https://jmirpublications.com/
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pdf
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application/pdf
Source:
JMIR Public Health Surveillance (October 21, 2021), v.7 issue 10
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