From the Introduction: "In January 2020, a previously unknown coronavirus strain was identified as the cause of a respiratory infection and death in humans. The first viral genome was sequenced using high throughput sequencing (HTS) from a sample collected in Wuhan, China. This virus, belonging to the viral species Severe acute respiratory syndrome- related coronavirus, has been subsequently named SARS-CoV-2 [severe acute respiratory syndrome coronavirus 2] and the associated disease coronavirus disease 2019 (COVID-19). Sequencing of (partial) genes and whole genomes (WGS) has been proven as a powerful method to investigate viral pathogen genomes, understand outbreak transmission dynamics and spill-over events and screen for mutations that potentially have an impact on transmissibility, pathogenicity, and/or countermeasures (e.g. diagnostics, antiviral drugs and vaccines). The results are key to informing outbreak control decisions in public health."
2021 European Centre for Disease Prevention and Control
European Centre for Disease Prevention and Control: https://www.ecdc.europa.eu/