Key Research Question: Are There Clinical Features That Reliably Indicate Need for Intubation and Mechanical Ventilation? Among Patients Requiring Intubation and Mechanical Ventilation, Are There Clinical Features That Predict Probability of Survival or Mortality? [open pdf - 276KB]
Key Messages from the Evidence Summary: " Several guidelines provide consensus based indications for intubation for patients with COVID-19 [coronavirus disease 2019], however there is no empirically-derived evidence to guide best practice to intubation/MV [mechanical ventilation] for patients with COVID-19.  Published mortality rates for intubated/MV patients with COVID-19 is estimated to be 40-70%.  Older patients and those with co-morbid conditions (cardiovascular disease, chronic respiratory disease, hypertension & diabetes) have higher mortality risk due to COVID-19, particularly after intubation and mechanical ventilation, however research continues to evolve.  Based on the high mortality rate for intubated/MV patients it is recommended clinicians consider early goals of care discussions with patients and families."
2020 Alberta Health Services. Posted here with permission. Document is under a Creative Commons license and requires proper attribution and noncommercial use to be shared: [https://creativecommons.org/licenses/by-nc-nd/4.0]
Alberta Health Services: https://www.albertahealthservices.ca/