ABSTRACT

Clinical Trials in Public Health Emergencies: The Ebola and COVID Experiences [video]   [open html - 0B]

From the Video Description: "Designing and implementing clinical trials for novel infectious disease treatments brings many challenges, especially during a rapidly evolving pandemic. A new disease brings uncertainties arising from an imperfect understanding about illness, limited information about proposed countermeasures, and complexities in measuring relevant patient outcomes. A pandemic adds an overloaded medical system with limited resources for research, heightened pressure to find cures quickly, and unpredictability about potential case numbers. I will discuss issues related to designing and conducting treatment trials in outbreaks of Ebola and COVID [coronavirus disease] based on my experience with three studies: Prevail II (the West African Ebola virus disease study of ZMapp), PALM (the Democratic Republic of the Congo Ebola virus disease study of ZMapp, mAb114, REGN-EB3 and remdesivir) and ACTT-1 (the multinational, platform COVID-19 study of remdesivir vs placebo)." The duration of the video is 57 minutes and 48 seconds.

Author:
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Date:
2020-05-13
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Copyright:
Public Domain
Retrieved From:
NIH VideoCasting: https://videocast.nih.gov/
Media Type:
text/html
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