Key Strategies to Enhance Infection Prevention and Antibiotic Stewardship: Report with Recommendations for Human and Animal Health   [open pdf - 4MB]

"The Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB) was established in 2015 in consultation with the Secretaries of Defense (DoD), Agriculture (USDA), and Health and Human Services (HHS) as part of a coordinated effort by the U.S. government to respond to the threat of antimicrobial resistance (AMR). Since its establishment in 2015, the PACCARB has created two reports. The first report evaluated the U.S. government's (USG) progress towards reducing and preventing the spread of AMR within the first 180-days of issuance of the National Action Plan on Combating Antibiotic-Resistant Bacteria (NAP). The second report proposed recommendations to incentivize the development of therapeutics, diagnostics, and vaccines for both humans and animals, while maximizing the return on investment (ROI) and encouraging appropriate stewardship and access to products. Building off the foundation of the first two PACCARB reports, the council has developed a high-level set of recommendations for effectively defining and evaluating the core principles of infection prevention and antibiotic stewardship (IP&AS). These recommendations are designed to ensure that the reduction and prevention of AMR in animals and people are conducted through well-supported federal and non-federal programs."

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