From the executive summary: "Drug overdose deaths in the United States more than tripled from 1999 to 2015. The current epidemic of drug overdoses began in the 1990s, driven by increasing deaths from prescription opioids that paralleled a dramatic increase in the prescribing of such drugs for chronic pain. In 2008, the number of deaths involving prescription opioids exceeded the number of deaths from heroin and cocaine combined. Since 2010, however, the U.S. has also seen sharp increases in deaths from heroin, synthetic opioids such as fentanyl, cocaine, and methamphetamine. [...] Morbidity and mortality statistics, however, fail to capture the full extent of the problem with substance use disorders in the United States. Survey data indicate that tens of millions of Americans misuse prescription opioids, sedatives, tranquilizers, and stimulants. Others use illicit drugs such as heroin, fentanyl, cocaine, and methamphetamine. Most persons using heroin have had a history of misusing prescription opioids first. [...] The purpose of this first annual surveillance report is to summarize the latest information available on the national level for various health outcomes, health behaviors, and prescribing patterns related to the drug problem in the United States. The most recent year of information available is different for different outcomes. The emphasis is on national information, but some state information is also presented. This document is intended to serve as a resource for persons charged with addressing this ongoing national problem. It will be updated annually."
Surveillance Special Report 1
Centers for Disease Control and Prevention: https://www.cdc.gov/