ABSTRACT

Use of Anthrax Vaccine in the United States: Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2009   [open pdf - 479KB]

"This statement 1) provides updated information on anthrax epidemiology; 2) summarizes the evidence regarding the effectiveness and efficacy, immunogenicity, and safety of AVA [anthrax vaccine adsorbed]; 3) provides recommendations for pre-event and preexposure use of AVA; and 4) provides recommendations for postexposure use of AVA. In certain instances, recommendations that did not change were clarified. No new licensed anthrax vaccines are presented. Substantial changes to these recommendations include the following: 1) reducing the number of doses required to complete the pre-event and preexposure primary series from 6 doses to 5 doses, 2) recommending intramuscular rather than subcutaneous AVA administration for preexposure use, 3) recommending AVA as a component of postexposure prophylaxis in pregnant womenexposed to aerosolized 'Bacillus anthracis' spores, 4) providing guidance regarding preexposure vaccination of emergency and other responder organizations under the direction of an occupational health program, and 5) recommending 60 days of antimicrobial prophylaxis in conjunction with 3 doses of AVA for optimal protection of previously unvaccinated persons after exposure to aerosolized 'B. anthracis' spores."

Author:
Publisher:
Date:
2010-07-23
Copyright:
Public Domain
Retrieved From:
Centers for Disease Control and Prevention: http://www.cdc.gov/
Format:
pdf
Media Type:
application/pdf
Source:
Morbidity and Mortality Weekly Report, Recommendations and Reports (July 23, 2010), v.59 no.RR-6
URL:
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