Congressional Budget Office Cost Estimate: H.R. 3537: Dangerous Synthetic Drug Control Act of 2016 [open pdf - 20KB]
"CBO [Congressional Budget Office] estimates that implementing H.R. 3537 would have no significant cost to the federal government. Enacting the bill could affect direct spending and revenues; therefore, pay-as-you-go procedures apply. However, CBO estimates that any effects would be insignificant. CBO estimates that enacting the legislation would not increase net direct spending or on-budget deficits in any of the four consecutive 10-year periods beginning in 2027. H.R. 3537 would expand the list of substances regulated under the Controlled Substances Act (title II of Public Law 91-513, the Comprehensive Drug Abuse Prevention and Control Act of 1970) to include cannabimimetic agents and other synthetic drugs. As a result, the government might be able to pursue cases involving drug use that it otherwise would not be able to prosecute. CBO expects that H.R. 3537 would apply to a relatively small number of additional offenders, however, so any increase in costs for law enforcement, court proceedings, or prison operations would not be significant. Any such costs would be subject to the availability of appropriated funds."
Congressional Budget Office: http://www.cbo.gov/