LLIS Lesson Learned: Biological Terrorism: Ensuring Adherence to Prescribed Prophylaxis Treatment   [open pdf - 56KB]

From the Summary: "During a suspected biological terrorist attack, public health officials must emphasize to patients receiving antibiotic prophylaxis treatment the importance of starting and continuing prescribed treatment." From the Description: "Following the death of a Connecticut woman from inhalational anthrax on November 21, 2001, the Connecticut Department of Public Health (CDPH) concentrated its anthrax identification and treatment efforts on the region's postal facilities. These efforts included setting up and managing prophylaxis clinics as well as conducting environmental sampling. Postal workers were given a ten-day supply of ciprofloxacin, and nasal swabs were collected at the clinics. All the nasal swabs tested negative for anthrax. No contamination was found in the regional post office; however, samples taken on November 28 and December 2 from four high-speed sorting machines in the regional distribution center tested positive for anthrax. Based on these results, the CDPH recommended that all postal employees at the regional facility receive a full, sixty-day treatment of prophylaxis. Ciprofloxacin treatment was later replaced by doxycycline."

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