NIAID Research Agenda for CDC Category A Agents Biodefense: Progress Report   [open pdf - 671KB]

"In February 2002, the National Institute of Allergy and Infectious Diseases convened the first Blue Ribbon Panel on Bioterrorism and Its Implications for Biomedical Research. This panel of experts was brought together by NIAID to provide objective expertise on the Institute's future counter-bioterrorism research agenda for anthrax, smallpox, botulism, plague, tularemia, and viral hemorrhagic fevers, the pathogens commonly referred to as CDC Category A agents. As a result of this meeting and the deliberations of the panel, a research agenda was developed and widely distributed to the scientific community. This agenda described the recommendations of the panel and NIAID's priorities for research on the Category A agents of bioterrorism (agenda available at http://www.niaid.nih.gov/biodefense/research/biotresearchagenda.pdf). Tremendous progress has been made in the year since this report was released. A significant area of early emphasis for NIAID has been establishment of the research infrastructure necessary to support studies of biodefense pathogens, such as biosafety containment laboratories. In addition, NIAID has worked to attract the long-term interest and support of industry and academia in developing biodefense countermeasures...This progress report describes the progress that has been made toward addressing the immediate goals outlined in the research agenda. The first section of this report reviews progress on meeting the general recommendations made by the panel that apply to all areas of NIAID biodefense research. Research goals specific to each of the Category A pathogens are covered in individual chapters. Finally, the progress made thus far on immunology as it relates to biodefense is described in a separate chapter." - From Introduction

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