"Biosafety in Microbiological and Biomedical Laboratories (BMBL) quickly became the cornerstone of biosafety practice and policy in the United States upon first publication in 1984. Historically, the information in this publication has been advisory in nature even though legislation and regulation, in some circumstances, have overtaken it and made compliance with the guidance provided mandatory. We wish to emphasize that the 5th edition of the BMBL remains an advisory document recommending best practices for the safe conduct of work in biomedical and clinical laboratories, from a biosafety perspective and is not intended as a regulatory document; though we recognize that it will be used that way by some. During the latest revision of the BMBL additional sections were added; sections on the principles and practices of biosafety and on risk assessment were expanded; all agent summary statements and appendices were revised; and effort was made to harmonize recommendations with guidance issued and regulations promulgated by other federal agencies. Wherever possible, an attempt was made to clarify both the language and intent of the information provided. The events of September 11, 2001 and the anthrax attacks in October of that year re-shaped and changed, forever, the way we manage and conduct work in biological and clinical laboratories and draw into focus the need for inclusion of additional information in the BMBL."
Centers for Disease Control and Prevention: http://www.cdc.gov/